RAWALPINDI, Pakistan (AP) - Pakistan opposition leader Benazir Bhutto was assassinated Thursday in a suicide attack that also killed at least 20 others at the end of a campaign rally, aides said.
"The surgeons confirmed that she has been martyred," Bhutto's lawyer Babar Awan said.
A party security adviser said Bhutto was shot in neck and chest as she got into her vehicle to leave the rally in Rawalpindi near the capital Islamabad. A gunman then blew himself up.
"At 6:16 p.m. she expired," said Wasif Ali Khan, a member of Bhutto's party who was at Rawalpindi General Hospital where she was taken after the attack.
Her supporters at the hospital began chanting "Dog, Musharraf, dog," referring to Pakistan's president Pervez Musharraf.
Some smashed the glass door at the main entrance of the emergency unit, others burst into tears. One man with a flag of Bhutto's Pakistan People's Party tied around his head was beating his chest.
In Washington, the State Department said it was seeking confirmation of Bhutto's condition.
"Certainly, we condemn the attack on this rally," deputy spokesman Tom Casey said. "It demonstrates that there are still those in Pakistan who want to subvert reconciliation and efforts to advance democracy."
The United States has for months been encouraging Musharraf to reach an accommodation with the opposition, particularly Bhutto, who was seen as having a wide base of support in Pakistan. Her party had been widely expected to do well in parliamentary elections set for next month.
At least 20 others were killed in the blast that took place as Bhutto left the rally where she addressed thousands of supporters in her campaign for Jan. 8 parliamentary elections.
Bhutto served twice as Pakistan's prime minister between 1988 and 1996. She had returned to Pakistan from an eight-year exile Oct. 18.
On the same day, her homecoming parade in Karachi was also targeted by a suicide attacker, killing more than 140 people. On that occasion she narrowly escaped injury.
President Bush, meanwhile, is demanding that those responsible for the assassination of Benazir Bhutto be brought to justice.
Bush spoke to reporters at his ranch in Crawford, Texas, Thursday morning, after the death of the former Pakistani prime minister who's been a leader of the opposition to President Pervez Musharraf.
Bush said the U.S. "strongly condemns" what he calls a "cowardly act by murderous extremists who are trying to undermine Pakistan's democracy."
He says, "Those who committed this crime must be brought to justice."
Bush expressed his condolences to Bhutto's family and to the families of others who were killed -- and to the people of Pakistan.
He called on them to honor Bhutto's memory by, in his words, "continuing with the democratic process for which she so bravely gave her life."
Editor's Note: Tonight on News 3 at 6, a national security expert from the Bush School at Texas A&M will offer insight on the implications of Bhutto's death and how it might affect the U.S.