The students who lost the most weight or body fat over the past 18 weeks will get money prizes.
At last week's final tally, the school's 215 students had lost a combined 852 pounds.
The boys' and girls' champions will be awarded 250 dollars, while the ten runners-up of each gender will get 100 dollars.
The Biggest Loser contest, which is being supported by corporate sponsorships, is based on the reality TV show of the same name.
Teacher Cathy Roach says the contest is a chance to educate students on healthy eating and exercise habits.
She says she wants to expand the contest next year to include teachers.