Officials at the Brazos County Community Emergency Operations Center say all shelters in the county are full.
Signage on Highways 6 and 21 is being changed to reflect that for drivers coming through the area.
Twelve churches, five schools and Reed Arena are currently sheltering individuals.
The CEOC worked with the school districts to make sure schools were cleared in order for classes to resume. Bryan and College Station's school districts have announced classes will resume Monday.